Found 11 matching trials
A Study of Recombinant Vaccinia Virus in Combination With Cemiplimab for Renal Cell Carcinoma PHASE1 This is a Phase 1b/2a, open-label, multi-center, dose-escalation and safety...
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Site 2644 University of California, Irvine
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Neoadjuvant Study of Recombinant Vaccinia Virus to Treat Metastatic Colorectal Carcinoma in Patients Undergoing Complete Resection of Liver Tumors PHASE2 This is a neoadjuvant Phase 2a, open-label trial in patients with metastati...
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Ottawa Hospital and Research Institute (OHRI)
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Safety Study of Recombinant Vaccinia Virus to Treat Refractory Solid Tumors PHASE1 This is a Phase I, open-label, dose-escalation trial in patients with advan...
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Recombinant Vaccinia Virus Administered Intravenously in Patients With Metastatic, Refractory Colorectal Carcinoma PHASE1 The purpose of this study is to evaluate the safety, tolerability, and effi...
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A Trial to Evaluate the Safety and Efficacy of the Combination of the Oncolytic Immunotherapy Pexa-Vec With the PD-1 Receptor Blocking Antibody Nivolumab in the First-line Treatment of Advanced Hepatocellular Carcinoma (HCC) PHASE1 This is a study to Evaluate the Safety and Efficacy of the Combination of t...
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A Study of Pexa-Vec (JX-594) Prior to Sorafenib to Treat Unresectable Primary Hepatocellular Carcinoma PHASE2 The purpose of this pilot safety study is to evaluate the safety and tolera...
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Pusan National University Hospital
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A Phase I/II Study of Pexa-Vec Oncolytic Virus in Combination With Immune Checkpoint Inhibition in Refractory Colorectal Cancer PHASE1 Background:
* Immune-based approaches in colorectal cancer have unfortunat...
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National Institutes of Health Clinical Center
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Safety Study of Recombinant Vaccinia Virus to Treat Refractory Solid Tumors in Pediatric Patients PHASE1 This is a Phase I, open-label, dose-escalation trial of JX-594 (Pexa-Vec) i...
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Cincinnati Children's Hospital Medical Center
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Phase 1b Dose Escalation Study of Intravenous JX-594 in Metastatic, Refractory Colorectal Carcinoma PHASE1 The purpose of this pilot safety study is to evaluate the safety and tolera...
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Samsung Medical Center
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Immunization Strategy With Intra-tumoral Injections of Pexa-Vec With Ipilimumab in Metastatic / Advanced Solid Tumors. PHASE1 The success of anti-CTLA4 therapy has inaugurated a paradigm shift in oncol...
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Institut Bergonie
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